The most severe reactions will occur when allergens are injected into the body and gain direct access to the blood stream. This access carries the danger of a generalized reaction, like anaphylaxis, which might be life-threatening. the subsequent are commonly injected allergens that may cause severe allergic reactions:
* Insect venom
* Medications
* Vaccines (including allergy shots)
* Hormones (for example, insulin)
In What we tend to Ingest
When foods or medications are ingested, allergens might gain access to the blood stream and become connected to specific IgE on cells in remote sites like the skin or nasal membranes. the flexibility of allergens to travel explains how symptoms will occur in areas apart from the gastrointestinal tract. Food allergy reactions might begin with tongue or throat swelling and will be followed by tingling, nausea, diarrhea, or abdomen cramps. Nasal respiration difficulties or skin reactions can also be seen. the 2 main allergen teams that are ingested are:
* Foods
* medicine (when taken by mouth): as an example, antibiotics and aspirin
Allergy Assist the foremost common foods that cause aversions are cow's milk, fish, shellfish, eggs, peanuts, tree nuts, soy, and wheat.
Touching Our Skin
Allergic contact dermatitis is an inflammation of the skin that's caused by an area aversion. the bulk of those localized skin reactions don't involve IgE, however are caused by cells of inflammation. The rash created is analogous to that of a poison ivy rash. It ought to be noted that when some allergens (for example, latex) return into contact with the skin, they're absorbed by the skin and might conjointly probably cause reactions throughout the body, not simply the skin. for many individuals, however, the skin may be a formidable barrier that may be solely domestically affected. samples of allergic contact dermatitis include:
* Latex (causes IgE and non-IgE reactions)
* Plants (poison ivy and oak)
* Dyes
* Chemicals
* Metals (nickel)
* Cosmetics
Allergic contact dermatitis doesn't involve IgE antibody, however involves cells of the immune system that are programmed to react when triggered by a sensitizing allergen. Touching or rubbing a substance to that you were previously sensitized will trigger a skin rash.
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